| Species/Subspecies:
|
Clostridium novyi |
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| Categories:
|
Spore forming; motile |
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| Etymology:
|
Genus name: a small spindle.
Species epithet: named after the American bacteriologist F.G. Novy. |
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| Significance: | [Important]
|
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| Taxonomy:
|
Class
Clostridia Order
Clostridiales Family
Clostridiaceae Genus
Clostridium |
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| Type Strain:
|
ATCC 17861 = NCTC 13029. |
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Macromorphology (smell):
 | Form medium sized colonies (1-5 mm in diameter), which can easily spread as a contiuous film over the entire plate (the bacteria "swarm"). |
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| Micromorphology:
| Large rods, which usually are motile. Produce oval spores, which are terminal or subterminal and may cause the cell to swell. |
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Gram +/Gram -:
 | G+ |
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| Metabolism:
|
Anaerobic |
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| Catalase/Oxidase: | -/- |
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| Other Enzymes:
| Esculinase -, lecithinase (+), tryptophanase (+). |
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| Fermentation of carbohydrates:
| D-glucose
? lactose
- maltose
v L-rhamnose
- sucrose
- L-arabinose
- cellobiose
- D-mannitol
- salicin
(-) trehalose
- glycerol
? inulin
- raffinose
- D-sorbitol
- starch
- |
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| Spec. Char.:
| |
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| Special Media:
| |
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| Disease: | Infectious necrotic hepatitis (black disease)
|
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| Hosts:
| Sheep, cattle |
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| Clinical Picture:
| |
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| Virulence Factors:
| Necrotizing α-toxin, β-toxin (lechitinase), γ-toxin (phopholipase C), δ-toxin (oxygen-labile hemolysin), ε-toxin (lipase), ζ-toxin (hemolysin), η toxin (tropomyosinase) and θ-toxin (lipase). |
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| Genome Sequence:
|
| Acc-no | Strain | Size (bp) | Genome |
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| NC_008593 | NT | 2 547 720 | 1 c + 0 |
|
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| 16S rRNA Seq.:
|
| Acc-no | Strain | Number of NT | Operon |
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| L37594 | ATCC 17861T | 1 452 | 10 |
|
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Taxonomy/phylogeny:
 |
About 180 differens species have been descibed within genus Clostridium. C. novyi is very closely related (phylogenetically) to C. botulinum group III and C. haemolyticum. |
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| Comment: | Two types of C. novyi, A and B, have been defined. Both type A and B produce α-toxin, but type A also produces γ-and ε-toxin. Some strains of type A also produces δ-toxin. Type B strains produce β-, ζ- and η-toxin. Some type B strains also produce θ-toxin. |
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| Reference(s):
| No. 33 |
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| Link:
| Clostridia.net |
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| Updated: | 2023-03-08 |
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