|Species/Subspecies:||Mycoplasma mycoides subsp. mycoides|
|Category:||Notifiable diseases and bacteria|
|Etymology:||Genus name: fungus shaped.|
Species epithet: similar to fungi.
Subspecies epithet: see Species epithet.
|Significance:||CBPP utrotades i de flesta europeiska länder runt år 1900, men sporadiska urbrott har förekommit i framför allt Italien, Portugal och Spanien. Det sista utbrottet rapporterades 1999 från Portugal. Sjukdomen medför idag mycket stora ekonomiska och sociala problem i Afrika.
|Type Strain:||PG1 = NCTC 10114.|
||Forms small and very typical umbonated colonies ("fried egg appearance"), which can be observed in a microscope.|
|Micromorphology:||Very small and pleomorphic. Nonmotile.|
|Gram +/Gram -:||G-, but is normally not gram stained because the cells will then be fragmented.|
|Spec. Char.:||Lacks a cell wall.|
|Disease:||Contagious bovine pleuropneumonia (CBPP).
|Hosts:||Cattle, water buffalo and yak.|
|Clinical Picture:||Elevated body temperature, passivity, ruminating ceases, coughing, difficulty in breathing, hunched back and wasting etc.|
|Virulence Factors:||Adhesion proteins, which make it possible for these bacteria to adhere to the host cell and the enzyme L-alpha-glycerophosphate oxidase, which makes it possible for these bacteria to transfer hydrogen peroxide (H2O2) into the host cell. The host cells will then die. Thus, in the presence of oxygen, hydrogen peroxide is formed when the enzyme converts glycerol-3-phosphate to glycerone phosphate.|
|16S rRNA Seq.:|
||About 125 species have been described within the genus Mycoplasma. M. mycoides subsp. mycoides belongs to the so-called mycoides group. These mycoplasmas are more closely related to mollicutes within the genus Spiroplasma, which are plant pathogens, than with most other members of the genus . See the phylogenetic tree.|
|Legislation:||CCPP is included in OIE's A-list of major animal diseases. The disease is in Sweden notifyable to the Swedish Board of Agriculture.|
|Comment:||The mollicutes lack a cell wall and have recently been transferred from the phylum Firmicutes to a new phylum, namely Tenericutes. Biotype SC (= M. mycoides subsp. mycoides) is the causative agent of CBPP. Biotype LC has been transferred to the subspecies M. mycoides subsp. capri.|
|Link:||Epiwebb - om epizootisjukdomar [in Swedish]|