|Categories:||Zoonotic; motile; notifiable diseases and bacteria|
|Etymology:||Genus name: thin helix (coil). |
Species epithet: interrogation (refers to the shape resembling a question mark).
|Significance:||Leptospirosis is said to be the most wide spread zoonotic infection in Nature.
|Type Strain:||Serovar Icterohaemorrhagiae, RGA = ATCC 23581.|
|Micromorphology:||"Sewing thread thin" (0.1 x 6-12 µm), helical and with a hook on each end. Motile and has two periplasmic flagella.|
|Gram +/Gram -:||G-|
|Fermentation of carbohydrates:||Does not ferment karbohydrates.|
|Spec. Char.:||Generation time: 6-8 h. Optimal growth temperature: 28-30°C.|
|Disease:||Leptospirosis, which is a zoonosis.
|Hosts:||Dog, cattle and pig etc. as well as humans.|
|Clinical Picture:||Fever, renal and hepatic insufficiency as well as pulmonary manifestations and reproductive failure.|
|16S rRNA Seq.:|
||About 25 different species have been described within the genus Leptispira. L. interrogans is closely related to L. kirschneri. See the phylogenetic tree (Fig. 116:1).|
|Legislation:||Leptospirosis is notifyable in Sweden|
|Comment:||There are 23 different serogroups, which in turn are divided into about 250 different serovars. Icterohaemorrhagiae and Bratislava are important serovars. From a clinical point of view, the serovar is more important than the species as pathogenicity is associated with serovar, rather than species and different species may belong to the same serovar.|
|Reference(s):||No. 6, 36, 41, 109, 139|
|Link:||The Leptospirosis Information Center|